Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10201/42568

Título: Nicotinamide N-Methyltransferase upregulation correlates with tumour differentiation in oral squamous cell carcinoma
Fecha de publicación: 2010
Editorial: Murcia : F. Hernández
ISSN: 0213-3911
Materias relacionadas: 61 - Medicina
Palabras clave: Nicotinamide
N-Methyltransferase
Resumen: We investigated expression levels of Nicotinamide N-Methyltransferase (NNMT), an enzyme involved in the biotransformation of many drugs and xenobiotic compounds, in oral squamous cell carcinoma (OSCC). Measurements were performed by immunohistochemistry and the relationship between tumour characteristics and NNMT levels in OSCC was studied to evaluate the effectiveness of NNMT as a prognostic marker in squamous cell carcinoma of the oral cavity. In conclusion, the present study suggests that NNMT may have potential as a biomarker and as a therapeutic target for OSCC.
Autor/es principal/es: Emanuelli, Monica
Santarelli, Andrea
Sartini, Davide
Ciavarella, Domenico
Rossi, Valentina
Pozzi, Valentina
Rubini, C.
Lo Muzio, L.
Forma parte de: Histology and histopathology
URI: http://hdl.handle.net/10201/42568
Tipo de documento: info:eu-repo/semantics/article
Número páginas / Extensión: 6
Derechos: info:eu-repo/semantics/openAccess
Aparece en las colecciones:Vol.25, nº1 (2010)



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