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| Título: | Nicotinamide N-Methyltransferase upregulation correlates with tumour differentiation in oral squamous cell carcinoma |
| Fecha de publicación: | 2010 |
| Editorial: | Murcia : F. Hernández |
| ISSN: | 0213-3911 |
| Materias relacionadas: | 61 - Medicina |
| Palabras clave: | Nicotinamide N-Methyltransferase |
| Resumen: | We investigated expression levels of Nicotinamide N-Methyltransferase (NNMT), an enzyme involved in the biotransformation of many drugs and xenobiotic compounds, in oral squamous cell carcinoma (OSCC). Measurements were performed by immunohistochemistry and the relationship between tumour characteristics and NNMT levels in OSCC was studied to evaluate the effectiveness of NNMT as a prognostic marker in squamous cell carcinoma of the oral cavity. In conclusion, the present study suggests that NNMT may have potential as a biomarker and as a therapeutic target for OSCC. |
| Autor/es principal/es: | Emanuelli, Monica Santarelli, Andrea Sartini, Davide Ciavarella, Domenico Rossi, Valentina Pozzi, Valentina Rubini, C. Lo Muzio, L. |
| Forma parte de: | Histology and histopathology |
| URI: | http://hdl.handle.net/10201/42568 |
| Tipo de documento: | info:eu-repo/semantics/article |
| Número páginas / Extensión: | 6 |
| Derechos: | info:eu-repo/semantics/openAccess |
| Aparece en las colecciones: | Vol.25, nº1 (2010) |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| Nicotinamide NMethyltransferase upregulation correlates with tumour differentiation in oral squamous cell carcinoma.pdf | 1,84 MB | Adobe PDF |  Visualizar/Abrir |
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