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| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.contributor.author | Obrdlik, A. | es |
| dc.contributor.author | Kukalev, A. | es |
| dc.contributor.author | Percipalle, P. | - |
| dc.date.accessioned | 2012-05-21T12:10:54Z | - |
| dc.date.available | 2012-05-21T12:10:54Z | - |
| dc.date.issued | 2007 | - |
| dc.identifier.issn | 0213-3911 | es |
| dc.identifier.uri | http://hdl.handle.net/10201/27633 | - |
| dc.description.abstract | Recent developments in the field of gene transcription regulation have unfolded a key role for actin as an important co-factor for all three eukaryotic RNA polymerases. In this review article we discuss the latest findings on actin in transcription of protein-coding and ribosomal genes, in complex with specific hnRNP proteins and a form of myosin 1ß which is entirely localized to the cell nucleus. Based on these recent studies, we propose a general model where actin may function in basal gene transcription as an allosteric regulator, to recruit transcriptional co-activators on active genes. A future challenge will be the identification of the polymerization state of actin in gene transcription and how it is mechanistically regulated. | - |
| dc.format | application/pdf | es |
| dc.format.extent | 5 | es |
| dc.language | eng | es |
| dc.publisher | Murcia : F. Hernández | es |
| dc.relation.ispartof | Histology and histopathology | es |
| dc.rights | info:eu-repo/semantics/openAccess | es |
| dc.subject | Nuclear actin | es |
| dc.subject | Ribonucleoproteins | es |
| dc.subject.other | 577 - Bioquímica. Biología molecular. Biofísica | es |
| dc.title | The function of actin in gene transcription | es |
| dc.type | info:eu-repo/semantics/article | es |
| Aparece en las colecciones: | Vol.22, nº 9 (2007) | |
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| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| The function of actin in gene transcription.pdf | 496,56 kB | Adobe PDF |  Visualizar/Abrir |
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