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Título: | Cox and mesothelioma: an overview |
Fecha de publicación: | 2005 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología |
Palabras clave: | Mesothelioma Chemotherapy |
Resumen: | Cyclooxygenases catalyze the rate limiting step in the production of prostanoids. Accumulating data demonstrate that overexpression of these enzymes, and in particular of cyclooxygenases-2, promotes multiple events involved in tumorigenesis; in addition, numerous studies show that inhibition of cyclooxygenases-2 can delay or prevent certain forms of cancer. Malignant mesothelioma is a lethal pleural, peritoneal and pericardial neoplasia that actually lacks valid therapies and in which cyclooxygenases-2 is recognized as an important adverse prognostic factor. Hence, there is an increasing interest in the development of new treatments based on cyclooxygenases-2 inhibitors, to prolong survival and even potentially cure this neoplasia. |
Autor/es principal/es: | Cardillo, I. Spugnini, E.P. Verdina, A. Galati, R. Citro, G. Baldi, A. |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/22554 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 8 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol.20, nº 4 (2005) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Cox and mesothelioma an overview.pdf | 184,94 kB | Adobe PDF | Visualizar/Abrir |
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