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dc.contributor.authorDavies, Grahames
dc.contributor.authorParr, C.-
dc.contributor.authorMason, M.D.-
dc.contributor.authorJenkins, S.A.-
dc.contributor.authorKynaston, H.G.-
dc.contributor.authorJiang, W.G.-
dc.description.abstractMen who die from prostate cancer do so from uncontrolled metastatic disease. A better understanding of the mechanisms involved in the progression and metastasis of prostate cancer may lead to novel therapeutic approaches to prevent its natural progression. Hepatocyte Growth Factor / Scatter factor (HGF/SF) has been demonstrated to elicit a number of key functions in numerous tissues that are important in the progression, invasion and metastasis of cancer. Studies have demonstrated that the activity of HGF/SF and its receptor c-Met are linked to disease progression in numerous cancers. However, research into these functions, which include activities as a mitogen, a motogen and an anti-apoptotic and angiogenic factor in prostate cancer are limited. This article reviews the published evidence of the roles HGF/SF plays in prostate cancer progression and highlights the clinical and therapeutic potential of research into this pleiomorphic
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.subjectHepatocyte growth factores
dc.subjectProstate canceres
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología::616.6 - Patología del sistema genitourinarioes
dc.titleHepatocyte growth factor/scatter factor and prostate cancer: a reviewes
Appears in Collections:Vol.20, nº 4 (2005)

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