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http://hdl.handle.net/10201/22507
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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Chung, Y.J. | es |
dc.contributor.author | Kim, J.W. | es |
dc.date.accessioned | 2011-06-30T12:00:41Z | - |
dc.date.available | 2011-06-30T12:00:41Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 0213-3911 | es |
dc.identifier.uri | http://hdl.handle.net/10201/22507 | - |
dc.description.abstract | Identification of robust diagnostic and therapeutic target molecules for human malignancy is still an important issue. If we identify novel proteins which play a stem-line role for cellular transformation or aggravation of malignancy, it could give us a clue to diagnose a tumor in an earlier stage and to develop more reliable therapeutic tools. For this purpose, we have screened abnormally expressed genes in various human cancers by differential display RT-PCR. One of the overexpressed genes was a human cervical cancer oncogene (HCCR). HCCR was not only identified in cervical cancer tissues, but also found to be overexpressed in various human malignancies such as leukemia/lymphoma, breast, kidney, stomach, colon, liver and ovarian cancer. This molecule appeared to be a negative regulator of p53. In this paper, we discuss the biological functions of HCCR molecules and its implications for early diagnosis and future development of therapeutic devices of cancer. | es |
dc.format | application/pdf | es |
dc.format.extent | 5 | es |
dc.language | eng | es |
dc.publisher | Murcia : F. Hernández | es |
dc.relation.ispartof | Histology and histopathology | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Oncogene | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina | es |
dc.title | Novel oncogene HCCR: its diagnostic and therapeutic implications for cancer | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol.20, nº 3 (2005) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Novel oncogene HCCR its diagnostic.pdf | 940,82 kB | Adobe PDF | ![]() Visualizar/Abrir |
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