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Título: Corneal endothelial cell density decreases with age in emmetropic eyes
Fecha de publicación: 2005
Editorial: Murcia : F. Hernández
ISSN: 0213-3911
Materias relacionadas: CDU::6 - Ciencias aplicadas::61 - Medicina::617 - Cirugía. Ortopedia. Oftalmología
Palabras clave: Emmetropia
Endothelial cell density
Resumen: Purpose: To analyze the corneal endothelial cell density in healthy adult emmetropic subjects. Methods: We analyzed the corneal endothelial cell density of a group made up of 225 emmetropic subjects (n=225). As age-matched control groups we analyzed two other groups, one made up of myopic subjects (n=209) and the other made up of hyperopic subjects (n=203). We recorded the mean of three consecutive measurements of the corneal endothelial cell density using the Topcon SP-2000P non-contact specular microscope (Topcon Corp., Tokyo, Japan). Results: The mean age was 38.6±11.8 years, 40.7±12.2 years, and 39.2±10.5 years for emmetropic, myopic and hyperopic subjects respectively (p=0.994). No significant differences (p=0.920) in endothelial cell density values were found between emmetropic (2985±245 cells/mm2), myopic (2936±258 cells/mm2) and hyperopic eyes (2946±253 cells/mm2). Lower corneal endothelial cell density values were found in older emmetropic (p<0.001), myopic (p<0.001), and hyperopic subjects (p<0.001). A significant correlation between endothelial cell density and age was found in emmetropic (r= -0.958; p<0.001), myopic (r= -0.954; p<0.001) and hyperopic subjects (r= -0.948; p<0.001). Conclusions: In healthy emmetropic subjects there is a reduction in corneal endothelial cell density with age although there are no differences in corneal endothelial cell density values between emmetropic, myopic and hyperopic subjects.
Autor/es principal/es: Sanchis-Gimeno, J.A.
Lleó-Pérez, A.
Alonso, L.M.
Rahhal, M.S.
Martínez Soriano, F.
Publicado en: Histology and histopathology
URI: http://hdl.handle.net/10201/22477
Tipo de documento: info:eu-repo/semantics/article
Número páginas / Extensión: 5
Derechos: info:eu-repo/semantics/openAccess
Aparece en las colecciones:Vol.20, nº 2 (2005)

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