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Título: | Effect of the arterial hypertension and captopril treatment on the angiotensin II content in the subfornical organ. A study in SHR rats |
Fecha de publicación: | 2005 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina |
Palabras clave: | Hypertension Captopril |
Resumen: | We studied the effects of spontaneous high blood pressure and the captopril treatment on the subfornical organ (SFO) of rats. The brains of control Wistar-Kyoto rats (WKY), WKY rats treated with captopril (WKY-T), spontaneously hypertensive rats (SHR) and SHR rats treated with captopril (SHR-T) were processed immunohistochemically using antiangiotensin II as primary antibody. Immunorective material (IRM) for angiotensin II was observed in a group of neurons and some cells of the ependymal layer of the SFO in WKY rats. The angiotensin II immunoreactive (AGII-ir) in the SHR rats was decreased, showing positive reaction only in a few neurons, while captopril treatment induced an increase in immunoreactive material in hypertensive rats, but contrarily, the expression of AGII-ir in the WKY-T group was scarce. The variations of the angiotensin II observed in the SFO could be owing to an interaction between the hypertension and its captopril treatment. |
Autor/es principal/es: | Carmona-Calero, E. Pérez-González, H. Martínez de la Peña y Valenzuela, Isabel Gonzalez-Marrero, I. Perez-Garcia, C.G. Marrero-Gordillo, N. Ormazabal-Ramos, C. Castañeyra Perdomo, A. Ferres Torres, R. |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/22446 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 4 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol.20, nº 1 (2005) |
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Effect of the arterial hypertension.pdf | 1,09 MB | Adobe PDF | Visualizar/Abrir |
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