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dc.contributor.authorPro, B.es
dc.contributor.authorDang, N.H.es
dc.date.accessioned2011-06-08T09:09:49Z-
dc.date.available2011-06-08T09:09:49Z-
dc.date.issued2004-
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/21644-
dc.description.abstractCD26/Dipeptidyl Peptidase IV (DPPIV) is a 110-kDa glycoprotein that is expressed on numerous cell types and has multiple biological functions. A key facet of CD26/DPPIV biology is its enzymatic activity and its physical and functional interaction with other molecules. The substrates of CD26/DPPIV are proline-containing peptides and include growth factors, chemokines, neuropeptides, and vasoactive peptides. DPPIV plays an important role in immune regulation, signal transduction, and apoptosis. Furthermore, CD26 appears to play an important role in tumor progression. In the present review, we summarize key aspects of CD26/DPPIV involvement in tumor biology and its potential role in cancer development and behavior.es
dc.formatapplication/pdfes
dc.format.extent7es
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectCanceres
dc.subjectTargeted therapyes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncologíaes
dc.titleCD26 dipeptidyl peptidase IV and its role in canceres
dc.typeinfo:eu-repo/semantics/articlees
Aparece en las colecciones:Vol.19, nº 4 (2004)

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