Por favor, use este identificador para citar o enlazar este ítem:
http://hdl.handle.net/10201/18512
Twittear
Título: | Hormonal receptors, cell proliferation fraction Ki-67 and c-erbB-2 amplification in breast cancer. Relationship between differentiation degree and ... |
Fecha de publicación: | 1994 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina |
Palabras clave: | Breast cancer Immunohistochemistry |
Resumen: | In view of the limitations of conventional prognostic factors such as differentiation degree, metastatic lymph nodes, hormonal receptors and others, especially when early lesions are found, additional new markers have been studied, such as gene amplification and cell proliferation index, in order to choose the appropriate treatment. Primary breast carcinoma tumors from 97 patients were examined for differentiation degree, metastatic lymph nodes, hormonal receptors, c-erbB-2 amplification and cell proliferation index (Ki-67). A negative relationship with hormonal receptors and c-erbB-2 amplification, Ki-67 and differentiation degree was found, whereas the relationship between c-erb13-2, Ki-67 and differentiation degree was positive. No relationship was found between these factors and metastatic lymph nodes. The concurrence of high cell proliferation index, cerbB- 2 amplification and negative hormonal receptor presence would indicate a subpopulation with a high risk of recurrence. But a larger survival study is necessary to correlate these factors with clinical outcome. |
Autor/es principal/es: | Sirvent, J.J. Santafe, M. Salvadó, M.T. Alvaro, T. Raventos, A. Palacios, J. |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/18512 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 8 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol. 9, nº 3 (1994) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
Hormonal receptors cell proliferation fraction Ki67 and cerbB2 amplification in breast cancer. Relationship between differentiation degree and ....pdf | 3,94 MB | Adobe PDF | Visualizar/Abrir |
Los ítems de Digitum están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.