Please use this identifier to cite or link to this item: http://hdl.handle.net/10201/18493

Title: Effects of prostaglandin Eq on the ultrastructure of the golden hamster parathyroid gland
Issue Date: 1994
Publisher: Murcia : F. Hernández
ISSN: 0213-3911
Related subjects: CDU::6 - Ciencias aplicadas::61 - Medicina
Keywords: Parathyroid gland
Large vacuolar body
Abstract: The effects of different ages on large vacuolar bodies in the parathyroid glands of golden hamsters after administration of prostaglandin E2 (PGE2) were investigated. In the parathyroid glands of the young and senile animals 15 min and the senile animals 60 min after administration of PGE2, the mean serum calcium concentration was significantly higher when compared to that of the young and senile control animals, respectively. In the experimental adult animals 60 min after administration of PGE2, the serum calcium concentration was seen to increase. In the parathyroid glands of the young animals 15 min and the adult and senile animals 60 min after administration of PGE2, the percent area occupied by large vacuolar bodies was significantly increased when compared to that of the young, adult and senile control animals, respectively. These findings suggest that the percent area occupied by large vacuolar bodies is increased in response to hypercalcemia induced by PGE2. It is thought that in the parathyroid glands suppressed by hypercalcemia there is a relationship between the percent area occupied by large vacuolar bodies and aging.
Primary author: Emura, S.
Utsumi, M.
Hayakawa, D.
Yamahira, T.
Terasawa, K.
Tamada, A.
Isono, H.
Shoumura, S.
Published in: Histology and histopathology
URI: http://hdl.handle.net/10201/18493
Document type: info:eu-repo/semantics/article
Number of pages / Extensions: 5
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:Vol. 9, nº 2 (1994)



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