Please use this identifier to cite or link to this item:

Title: Morphometrical changes in the rat thymic lymphoid cells after treatment with two different doses of estradiol benzoate
Issue Date: 1994
Publisher: Murcia : F. Hernández
ISSN: 0213-3911
Related subjects: CDU::6 - Ciencias aplicadas::61 - Medicina
Keywords: Thymus
Sex steroids
Abstract: In the present study we have evaluated morphometrically the contribution of thymocytes to the thymic involution induced by a single injection either of 100 pg or 500 pg of estradiol benzoate. Our results demonstrate that changes in the numbers of both cortical and medullary thymocytes contribute to thymic involution although the importance of the first is quantitatively higher. On the other hand, while cortical pyknosis and a decreased mitotic index could be important for explaining the estrogen-dependent thymic changes, the release of lymphocytes from thymus seems to be the main factor inducing the thymic involution as well as the lack of recovery observed at the end of the experimental period.
Primary author: Martin, A.
Alonso, L.M.
Gomez del Moral, M.
Zapata, A.G.
Published in: Histology and histopathology
Document type: info:eu-repo/semantics/article
Number of pages / Extensions: 6
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:Vol. 9, nº 2 (1994)

Items in Digitum are protected by copyright, with all rights reserved, unless otherwise indicated.