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Título: | Morphometrical changes in the rat thymic lymphoid cells after treatment with two different doses of estradiol benzoate |
Fecha de publicación: | 1994 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina |
Palabras clave: | Thymus Sex steroids |
Resumen: | In the present study we have evaluated morphometrically the contribution of thymocytes to the thymic involution induced by a single injection either of 100 pg or 500 pg of estradiol benzoate. Our results demonstrate that changes in the numbers of both cortical and medullary thymocytes contribute to thymic involution although the importance of the first is quantitatively higher. On the other hand, while cortical pyknosis and a decreased mitotic index could be important for explaining the estrogen-dependent thymic changes, the release of lymphocytes from thymus seems to be the main factor inducing the thymic involution as well as the lack of recovery observed at the end of the experimental period. |
Autor/es principal/es: | Martin, A. Alonso, L.M. Gomez del Moral, M. Zapata, A.G. |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/18488 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 6 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol. 9, nº 2 (1994) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Morphometrical changes in the rat thymic lymphoid cells after treatment with two different doses of estradiol benzoate.pdf | 2,88 MB | Adobe PDF | Visualizar/Abrir |
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