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Title: ImmunohistochemicaI-morphometric study of the LH-adenohypophyseal cells following chronic treatment with met-enkephalin
Issue Date: 1994
Publisher: Murcia : F. Hernández
ISSN: 0213-3911
Related subjects: CDU::6 - Ciencias aplicadas::61 - Medicina
Keywords: LH
Abstract: In order to test the possible effect of chronic treatment with met-enkephalin upon the LHadenohypophyseal cells, an imrnunohistochemicalmorphometric study was carried out in rats of both sexes receiving a daily dose of 40 pg of met-enkephalin intramuscularly over 15 days. Following the administration of the opioid, a drastic decrease in the cellular, cytoplasmic and nuclear areas when compared to the normal and control animals was detected. Morphologically, the main finding in males was the appearance of irregularly-shaped pseudovacuolated cells. On the other hand, in females a decrease in the intensity of reaction was found. These results strongly suggest a decrease in the activity of the LH-adenohypophyseal cells following chronic administration of met-enkephalin.
Primary author: Rubio, M.
Sanchez, F.
Carretero, J.
Riesco, J. M.
Cabo, L.
Vazquez, R.
Published in: Histology and histopathology
Document type: info:eu-repo/semantics/article
Number of pages / Extensions: 6
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:Vol. 9, nº 2 (1994)

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