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|Title:||ImmunohistochemicaI-morphometric study of the LH-adenohypophyseal cells following chronic treatment with met-enkephalin|
|Publisher:||Murcia : F. Hernández|
|Related subjects:||CDU::6 - Ciencias aplicadas::61 - Medicina|
|Abstract:||In order to test the possible effect of chronic treatment with met-enkephalin upon the LHadenohypophyseal cells, an imrnunohistochemicalmorphometric study was carried out in rats of both sexes receiving a daily dose of 40 pg of met-enkephalin intramuscularly over 15 days. Following the administration of the opioid, a drastic decrease in the cellular, cytoplasmic and nuclear areas when compared to the normal and control animals was detected. Morphologically, the main finding in males was the appearance of irregularly-shaped pseudovacuolated cells. On the other hand, in females a decrease in the intensity of reaction was found. These results strongly suggest a decrease in the activity of the LH-adenohypophyseal cells following chronic administration of met-enkephalin.|
|Primary author:||Rubio, M.|
Riesco, J. M.
|Published in:||Histology and histopathology|
|Number of pages / Extensions:||6|
|Appears in Collections:||Vol. 9, nº 2 (1994)|
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