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Título: | Ultrastructural relations between nigrostriatal dopaminergic neurons and cholinergic nerve endings in the human brain |
Fecha de publicación: | 1993 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina |
Palabras clave: | Human Substantia nigra |
Resumen: | The connections between cholinergic nerve endings anct nigrostriatal dopaminergic neurons were s t ~ ~ d i ei nd the substantia nigra pars compacta of the human brain. Irnmunocytochemistry of tyrosine hydroxylase followed by ionic fixation of acetylcholinelike cation i l l synaptic vesicles allowed dopaminergic neurons and cholinergic nerve endings to be visualized on the same ultrathin section. Numerous contacts, some of them with synaptic structures, were observed between nerve endings, with or without precipitates of acetylcholine-like cation and dendrites or cell bodies of tyrosine hydroxylase-inimunoreactive neurons. These results, which agree with previous studies performed in the rat. suggest that cholinergic nerve endings control the activity of the nigrostriatal neurons at the level of the dendrites and cell bodies in the substantia nigra. |
Autor/es principal/es: | Anglade, P. Tsuji, S. Hirsch, E.C. Javoy-Agid, F. Agid, Y. |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/18431 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 4 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol. 8, nº 3 (1993) |
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Ultrastructural relations between nigrostriatal dopaminergic neurons and cholinergic nerve endings in the human brain.pdf | 2,13 MB | Adobe PDF | Visualizar/Abrir |
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