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Título: Small cell carcinoma of the stomach: An immunohistochemical and electron microscopic study
Fecha de publicación: 1992
Editorial: Murcia : F. Hernández
ISSN: 0213-3911
Materias relacionadas: CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología
Palabras clave: Small cell carcinoma
Desmin
Resumen: A 4 x 6 cm ulcerative mass in the antrum was found to consist of papillary adenocarcinoma in the surrounding wall and the small round cell neoplasm at its base. Immunohistochemical staining revealed that elements of the papillary adenocarcinoma were positive for carcinoembryonic antigen, epithelial membrane antigen, keratin, endocrine granule constituent, and CA19-9, while components of the small cell carcinoma were weakly positive only for neuron-specific enolase. In one portion of the small cell carcinoma, particularly large cells with pleomorphic nuclei which were intensely positive for desmin were detected. Electron microscopic examination revealed dense-cored granules and intercellular junctions in the small neoplastic cells and bundles of intermediate filaments in the desmin-positive large cells. These findings suggest that ultrastmctural examination is vital in diagnosis of smail cell carcinoma and they reveal the capability of this carcinoma toward multidirectional differentiation.
Autor/es principal/es: Morikawa, Y.
Tohya, K.
Matsuura, N.
Matsumoto, K.
Kakudo, K.
Forma parte de: Histology and histopathology
URI: http://hdl.handle.net/10201/18342
Tipo de documento: info:eu-repo/semantics/article
Número páginas / Extensión: 6
Derechos: info:eu-repo/semantics/openAccess
Aparece en las colecciones:Vol. 7, nº 4 (1992)

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