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dc.contributor.authorMatsuura, N.-
dc.contributor.authorMatsumoto, K.-
dc.contributor.authorKakudo, K.-
dc.description.abstractA 4 x 6 cm ulcerative mass in the antrum was found to consist of papillary adenocarcinoma in the surrounding wall and the small round cell neoplasm at its base. Immunohistochemical staining revealed that elements of the papillary adenocarcinoma were positive for carcinoembryonic antigen, epithelial membrane antigen, keratin, endocrine granule constituent, and CA19-9, while components of the small cell carcinoma were weakly positive only for neuron-specific enolase. In one portion of the small cell carcinoma, particularly large cells with pleomorphic nuclei which were intensely positive for desmin were detected. Electron microscopic examination revealed dense-cored granules and intercellular junctions in the small neoplastic cells and bundles of intermediate filaments in the desmin-positive large cells. These findings suggest that ultrastmctural examination is vital in diagnosis of smail cell carcinoma and they reveal the capability of this carcinoma toward multidirectional
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.subjectSmall cell carcinomaes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncologíaes
dc.titleSmall cell carcinoma of the stomach: An immunohistochemical and electron microscopic studyes
Appears in Collections:Vol. 7, nº 4 (1992)

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