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Título: | Alteration of primate ovary surface epithelium by exposure to hexachlorobenzene: A quantitative study |
Fecha de publicación: | 1991 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina::611 - Anatomía |
Palabras clave: | Monkey ovary Hexachlorobenzene |
Resumen: | Hexachlorobenzene (HCB) is a fungicide and a pollutant of increasing concern in industrialized regions of the world. Reproductive failure is one of the effects of HCB upon mammals. Alteration of cell shape in the ovary surface epithelium (OSE) of Cynomolgus monkeys following oral administration of HCB was observed in this study. At the lowest dose used, 0.1 mgl kg body weight, a dosage that is associated with follicular degeneration, HCB caused quantifiable changes in length-to-width ratios of OSE. Measurement of cell shape by light microscopy offers a reliable indication of OSE changes induced by HCB. |
Autor/es principal/es: | Sims, David E. Singh, Amreek Donald, Alan Jarrell, John Villeneuve, David C. |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/18272 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 5 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol. 6, nº 4 (1991) |
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