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Título: | Warthin's tumor as a hamartomatous dysplastic lesion: a histochemical and immunohistochemical study |
Fecha de publicación: | 1991 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología |
Palabras clave: | Warthin's tumor Salivary gland |
Resumen: | The etiology of Warthin's tumor was sought by histochemical and immunohistochemical methods using 7 surgically extirpated samples and normal salivary glands as a control for the epithelial component. All the samples exhibited a variety of amyloid deposition in the interfollicular area of the lymphoid component. The interfollicular lymphoid cells were both T-cells and cells of B-cell lineage with an almost l to 2 population ratio. Most antigen-positive B-cells were plasma cells that exhibited polyclonality of irnmunoglobulin. B-cells were also present in the lymphoid mantles and a few were found in the germinal centres. The epithelial component exhibited mucinous and proteinaceous fluid in the lumen and varied immunohistological reactions; being particularly positive to carcinoembryonic antigen, S-100 protein, and B-cell antigen; quite similar to that of normal salivary duct cells. The results suggest that Warthin's tumor may not be a hamartomatous neoplasm at all but a hamartomatous dysplastic lesion. |
Autor/es principal/es: | Takaaki Ohmori Uraga, Naomi Tabei, Ryo |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/18270 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 7 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol. 6, nº 4 (1991) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Warthins tumor as a hamartomatous dysplastic lesion a histochemical and immunohistochemical study.pdf | 726,69 kB | Adobe PDF | Visualizar/Abrir |
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