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Título: Warthin's tumor as a hamartomatous dysplastic lesion: a histochemical and immunohistochemical study
Fecha de publicación: 1991
Editorial: Murcia : F. Hernández
ISSN: 0213-3911
Materias relacionadas: CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología
Palabras clave: Warthin's tumor
Salivary gland
Resumen: The etiology of Warthin's tumor was sought by histochemical and immunohistochemical methods using 7 surgically extirpated samples and normal salivary glands as a control for the epithelial component. All the samples exhibited a variety of amyloid deposition in the interfollicular area of the lymphoid component. The interfollicular lymphoid cells were both T-cells and cells of B-cell lineage with an almost l to 2 population ratio. Most antigen-positive B-cells were plasma cells that exhibited polyclonality of irnmunoglobulin. B-cells were also present in the lymphoid mantles and a few were found in the germinal centres. The epithelial component exhibited mucinous and proteinaceous fluid in the lumen and varied immunohistological reactions; being particularly positive to carcinoembryonic antigen, S-100 protein, and B-cell antigen; quite similar to that of normal salivary duct cells. The results suggest that Warthin's tumor may not be a hamartomatous neoplasm at all but a hamartomatous dysplastic lesion.
Autor/es principal/es: Takaaki Ohmori
Uraga, Naomi
Tabei, Ryo
Publicado en: Histology and histopathology
URI: http://hdl.handle.net/10201/18270
Tipo de documento: info:eu-repo/semantics/article
Número páginas / Extensión: 7
Derechos: info:eu-repo/semantics/openAccess
Aparece en las colecciones:Vol. 6, nº 4 (1991)

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