Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10201/17943

Título: Electron microscopic pathological patterns of alveolar septum in acute dextran-induced and alloxan-induced pulmonary edema in dogs
Fecha de publicación: 1988
Editorial: Murcia : F. Hernández
ISSN: 0213-3911
Materias relacionadas: CDU::6 - Ciencias aplicadas::61 - Medicina
Palabras clave: Pulmonary edema
Dextran-induced edema
Resumen: We studied the incidence of electron microscopic pathological patterns of the alveolar septum observed 30 min after induction of pulrnonary edema by dextran-70 infusion (6 dogs, dextran group) and by alloxan injection (6 dogs, alloxan group). For comparable amounts of extravascular lung water in both dextran and alloxan groups, which were twice as much as control group (6 dogs), we characterized the pathological changes. The incidence of the electron microscopic pathological patterns that appeared in dextran group compared with that in control group was significantly high in terms of the widening of the interstitial space. dispersion and disarray of collagen fibrils, and erythrocytes in the interstitial space. The incidence in alloxan group compared with that in control group was significantly high in terms of the swelling of epithelial cells and endothelial cells as well as the widening of the interstitial space, and dispersion and disarray of collagen fibrils. We conclude that dextran causes interstitial changes exclusively and alloxan causes cellular changes primarily coupled with secondary interstitial changes in acute pulmonary edema.
Autor/es principal/es: Koji Nakahara
Michio Arakawa
Kenjiro Kambara
Hiroshi Oda
Senri Hirakawa
Shizuko Shoumura
Hideo Isono
Forma parte de: Histology and histopathology
URI: http://hdl.handle.net/10201/17943
Tipo de documento: info:eu-repo/semantics/article
Número páginas / Extensión: 10
Derechos: info:eu-repo/semantics/openAccess
Aparece en las colecciones:Vol. 3, nº 4 (1988)



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