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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Barbareschi, M. | es |
dc.contributor.author | Mauri, M.F. | es |
dc.contributor.author | Muscara, M. | - |
dc.contributor.author | Lo Re, V. | - |
dc.date.accessioned | 2011-01-17T12:39:52Z | - |
dc.date.available | 2011-01-17T12:39:52Z | - |
dc.date.issued | 1987 | - |
dc.identifier.issn | 0213-3911 | es |
dc.identifier.uri | http://hdl.handle.net/10201/17862 | - |
dc.description.abstract | A group of lung neuroendocrine (NE) neoplasms are investigated in view of the possible presence of S-100 protein immunoreactivity in their cells. The selected tumours were classified according to Gould et al. (1983a) and Mosca et al. (1985). They comprise 5 carcinoids, 3 neuroendocrine carcinomas of the well-differentiated type, or peripheral carcinoids, 5 neuroendocrine carcinomas of the intermediate cell type, or intermediate-cell, poorly differentiated carcinomas, 3 neuroendocrine carcinomas of the microcytoma type, or small cell carcinomas-SCC and a nodal metastasis of microcytoma. All but 2 tumours were immunoreactive for neuron specific enolase (NSE). Few S-100 immunoreactive cells were detected in 4 out of 5 carcinoids, in 1 out of 3 peripheral carcinoids, in 4 out of 5 poorly differentiated carcinomas and in the 3 microcytomas examined. No S-100 positive cells were found in the SCC's nodal metastasis. The S-100 immunolabelled cells can be interpreted as dendritic reticulum cells migrating through the tumours. However, in one case of typical carcinoid, abundant S-100 positive cells were detected: their stellate morphology and their intimate relation with neoplastic cells suggest that they are part of the neoplasia as a sort of satellite cell. | en_EN |
dc.format | application/pdf | es |
dc.format.extent | 8 | es |
dc.language | eng | es |
dc.publisher | Murcia : F. Hernández | es |
dc.relation.ispartof | Histology and histopathology | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Lung neuroendocrine tumours | es |
dc.subject | S-100 protein | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina | es |
dc.title | S-100 protein in human lung neuroendocrine neoplasms. Immunohistochemical study of 14 cases and review of the literature | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol. 2, nº 2 (1987) |
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S100 protein in human lung neuroendocrine neoplasms. Immunohistochemical study of 14 cases and review of the literature.pdf | 565,31 kB | Adobe PDF | Visualizar/Abrir |
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