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Título: | Light and electron microscopic study of fetal lung following maternal exposure to methylmercuric chloride |
Fecha de publicación: | 1987 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina::611 - Anatomía |
Palabras clave: | Fetal lung Methylmercuric chloride |
Resumen: | Varying dose levels of methylmercuric chloride (MMC), 1000 ppm (5 mg through 15 mglkg of body weight), were administered via an intragastric tube to pregnant ICR SwissIWebster mice on day 9 of gestation. The animals were killed on gestational day 18 and the fetuses removed. Fetal lung sections were processed for light and electron microscopy. A group of animals treated with physiological saline in a similar mannner served as the controls. The fetal lungs from treated animals were hypoplastic and retarded in development. The severity of pulmonary changes increased with the dose-levels of MMC. Vacuolation and lysis of mitochondria were seen in fetal lungs. Mitochondrial damage increased in severity with doselevel of methylmercuric chloride. |
Autor/es principal/es: | Curle, D.C. Ray, M. Persaud, T.V.N. |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/17861 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 6 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol. 2, nº 2 (1987) |
Ficheros en este ítem:
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Light and electron microscopic study of fetal lung following maternal exposure to methylmercuric chloride.pdf | 455,65 kB | Adobe PDF | Visualizar/Abrir |
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