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Título: | Observations on cell kinetics and viability of a human melanoma cell line exposed to dicarboxylic acids in tissue culture |
Fecha de publicación: | 1986 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología::616.5 - Piel. Dermatología clínica |
Palabras clave: | Melanoma Dicarboxylic acids |
Resumen: | Cultures of human nlelanonla cell line BOO08 \verc e-iposed to the disodium salts of arelaic acid (C,, 2Na), adipic acid (C,, 2Na) and dodecanediaic acid (C,, 2Na) at IO'M and 5 x 10-'M for 24 hrs. None of the diacid salts had a significant effect on growth rate or viability of the cells, at 10-'M for 24 hrs nor had C, 2Na any effect at 5 x 10'M. At 5 x 102M for 24 hrs, both C,, 2Na, and CIL2 Na had a significant effect in reducing both growth and viability. These effects were accompanied by morphological evidence of cell death, and swelling of mitochondria and accuni~~latioonf lipid droplets within cytoplasm of still biable cells. |
Autor/es principal/es: | Breathnach, A. S. Robins, E.J. Bhasin, Y. P. Ethridge, L. B. Nazzaro-Porro, M. Passi, S. Picardo, M. |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/17825 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 5 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol. 1, nº 3 (1986) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Observations on cell kinetics and viability of a human melanoma cell line exposed to dicarboxylic acids in tissue culture.pdf | 427,33 kB | Adobe PDF | Visualizar/Abrir |
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