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https://doi.org/10.1016/j.cell.2017.08.008
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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Rosenzweig, Elizabeth | - |
dc.contributor.author | Xu, Bin | - |
dc.contributor.author | Kuhn, Luis | - |
dc.contributor.author | Martinez-Sanchez, Antonio | - |
dc.contributor.author | Schaffer, Miroslava | - |
dc.contributor.author | Strauss, Mike | - |
dc.contributor.author | Cartwright, Heather | - |
dc.contributor.author | Ronceray, Pierre | - |
dc.contributor.author | Plitzko, Jürgen | - |
dc.contributor.author | Förster, Friedrich | - |
dc.contributor.author | Wingreen, Ned | - |
dc.contributor.author | Engel, Benjamin | - |
dc.contributor.author | Mackinder, Luke | - |
dc.contributor.author | Jonikas, Martin | - |
dc.contributor.other | Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Ingeniería de la Información y las Comunicaciones | es |
dc.date.accessioned | 2023-12-20T10:10:33Z | - |
dc.date.available | 2023-12-20T10:10:33Z | - |
dc.date.issued | 2017-09-21 | - |
dc.identifier.citation | Cell, Vol. 171, Issue 1, 21 September 2017, Pages 148-162.e19 | es |
dc.identifier.issn | Print: 0092-8674 | - |
dc.identifier.issn | Electronic: 1097-4172 | - |
dc.identifier.uri | http://hdl.handle.net/10201/136773 | - |
dc.description | © 2017. Elsevier Inc.. This document is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This document is the accepted version of a published Work that appeared in final form in Cell. To access the final edited and published work see https://doi.org/10.1016/j.cell.2017.08.008 | es |
dc.description.abstract | Approximately 30%–40% of global CO2 fixation occurs inside a non-membrane-bound organelle called the pyrenoid, which is found within the chloroplasts of most eukaryotic algae. The pyrenoid matrix is densely packed with the CO2-fixing enzyme Rubisco and is thought to be a crystalline or amorphous solid. Here, we show that the pyrenoid matrix of the unicellular alga Chlamydomonas reinhardtii is not crystalline but behaves as a liquid that dissolves and condenses during cell division. Furthermore, we show that new pyrenoids are formed both by fission and de novo assembly. Our modeling predicts the existence of a “magic number” effect associated with special, highly stable heterocomplexes that influences phase separation in liquid-like organelles. This view of the pyrenoid matrix as a phase-separated compartment provides a paradigm for understanding its structure, biogenesis, and regulation. More broadly, our findings expand our understanding of the principles that govern the architecture and inheritance of liquid-like organelles. | es |
dc.format | application/pdf | es |
dc.format | video/mp4 | es |
dc.format.extent | 34 | es |
dc.language | eng | es |
dc.publisher | Elsevier | es |
dc.relation | This work was supported by the National Science Foundation (EF-1105617 and IOS-1359682 to M.C.J. and PHY-1305525 to N.S.W.), the Carnegie Institution for Science (to L.C.M.M. and M.C.J.); NIH (T32GM007276 to E.S.F.R. and 7DP2GM119137-02 to M.C.J.), the Simons Foundation and HHMI (55108535), and Princeton University (to M.C.J.), a CONACyT-DAAD Graduate Scholarship (to L.K.C), a Fundación Séneca Postdoctoral Fellowship (to A.M.-S.), an Alexander von Humboldt Foundation Postdoctoral Fellowship (to B.D.E), and the Deutsche Forschungsgemeinschaft (FO 716/4-1 to F.F.). | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Organelle inheritance | es |
dc.subject | Liquid-like organelles | es |
dc.subject | Biological phase transitions | es |
dc.subject | Carbon fixation | es |
dc.subject | Chlamydomonas reinhardtii | es |
dc.subject | Magic numbers | es |
dc.subject | Cryo-electron tomography | es |
dc.subject | Rubisco | es |
dc.subject | CO2 concentrating mechanism | es |
dc.subject | Pyrenoid | es |
dc.title | The Eukaryotic CO2-Concentrating Organelle Is Liquid-like and Exhibits Dynamic Reorganization | es |
dc.type | info:eu-repo/semantics/article | es |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S0092867417309339/pdfft?md5=1c896bacbb0c78a3e8cb8f66791e9c05&pid=1-s2.0-S0092867417309339-main.pdf | es |
dc.identifier.doi | https://doi.org/10.1016/j.cell.2017.08.008 | - |
Aparece en las colecciones: | Artículos: Ingeniería de la Información y las Comunicaciones |
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Fichero | Descripción | Tamaño | Formato | |
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Cell_2017b_author_manuscript.pdf | 4,77 MB | Adobe PDF | ![]() Visualizar/Abrir |
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