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DOI: 10.14670/HH-18-028
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Akiyama, Yoshiyuki | - |
dc.contributor.author | Homma, Yukio | - |
dc.contributor.author | Maeda, Daichi | - |
dc.date.accessioned | 2022-06-03T09:14:13Z | - |
dc.date.available | 2022-06-03T09:14:13Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | Histology and Histopathology, Vol.34, nº1, (2019) | es |
dc.identifier.issn | 1699-5848 | - |
dc.identifier.issn | 0213-3911 | - |
dc.identifier.uri | http://hdl.handle.net/10201/120922 | - |
dc.description.abstract | Interstitial cystitis/bladder pain syndrome (IC/BPS) is an umbrella term of chronic debilitating conditions of unknown etiology characterized by symptoms of lower urinary tract hypersensitivity such as bladder pain/discomfort, urgency, and urinary frequency. The pathological features of IC/BPS have been generally reported as non-specific chronic inflammatory changes, with mast cell infiltration as a potential key finding. However, growing evidence reveals a histological distinction between IC/BPS with Hunner lesions and IC/BPS without Hunner lesions, and also sheds doubt on the diagnostic value of the mast cell count. Specifically, IC/BPS with Hunner lesions is an inflammatory disorder characterized by pancystitis with B cell abnormalities and epithelial denudation, while IC/BPS without Hunner lesions shows minimal histological changes. The umbrella term “IC/BPS” connects totally distinct clinical entities. Pathological evaluation thus plays an important role in the precise subtyping and clinical management of IC/BPS. In addition, terminology should be developed to refer separately to IC/BPS with Hunner lesions and IC/BPS without Hunner lesions | es |
dc.format | application/pdf | es |
dc.format.extent | 8 | es |
dc.language | eng | es |
dc.publisher | Universidad de Murcia. Departamento de Biología Celular e Histología | es |
dc.relation | Sin financiación externa a la Universidad | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Interstitial cystitis | es |
dc.subject | Bladder pain syndrome | es |
dc.subject | Terminology | es |
dc.subject | B cell | es |
dc.subject | Plasma cell | es |
dc.subject | Mast cell | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología | es |
dc.title | Pathology and terminology of interstitial cystitis/bladder pain syndrome: A review | es |
dc.type | info:eu-repo/semantics/article | es |
dc.identifier.doi | DOI: 10.14670/HH-18-028 | - |
Aparece en las colecciones: | Vol.34, nº1 (2019) |
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Akiyama-34-25-32-2019.pdf | 3,25 MB | Adobe PDF | Visualizar/Abrir |
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