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http://hdl.handle.net/10201/27575
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Título: | Primary mammary osteogenic sarcoma |
Fecha de publicación: | 2007 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | 616 - Patología. Medicina clínica. Oncología |
Palabras clave: | Extraskeletal osteosarcoma Mammary gland |
Resumen: | A 78 year-old female patient underwent a total mastectomy with axillary lymph node dissection for a primary breast osteosarcoma. Microscopically the tumor was identical to grade II skeletal osteosarcoma. Immunohistochemically no reactivity was detected, either for the epithelial markers EMA, AE1/AE3, CK8, 18, 19, or for HER-2/neu, estrogen and progesterone receptors, as well as fluorescent IN SITU hybridization for HER-2/neu. The diagnosis of this tumor fulfills certain clinicopathological criteria. Mammary osteosarcoma is usually developed in phyllodes tumors or carcinosarcomas of the breast as a result of metaplasia of the epithelial component. This rare tumor of the breast is occasionally associated with prior radiation therapy or well documented trauma. Mammary osteosarcoma is a biologically aggressive neoplasm with a 38% five-year survival rate. Surgical resection is the most effective therapy to date. Adjuvant treatment -chemotherapy or radiotherapy- has shown no clear benefit. An extensive review of the literature is also presented. |
Autor/es principal/es: | Khaldi, L. Athanasiou, E.T. Hadjitheofilou, C.Th. |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/27575 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 5 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol.22, nº 4 (2007) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Primary mammary osteogenic sarcoma.pdf | 2,32 MB | Adobe PDF | ![]() Visualizar/Abrir |
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