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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Khaldi, L. | es |
dc.contributor.author | Athanasiou, E.T. | es |
dc.contributor.author | Hadjitheofilou, C.Th. | - |
dc.date.accessioned | 2012-05-21T12:09:20Z | - |
dc.date.available | 2012-05-21T12:09:20Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 0213-3911 | es |
dc.identifier.uri | http://hdl.handle.net/10201/27575 | - |
dc.description.abstract | A 78 year-old female patient underwent a total mastectomy with axillary lymph node dissection for a primary breast osteosarcoma. Microscopically the tumor was identical to grade II skeletal osteosarcoma. Immunohistochemically no reactivity was detected, either for the epithelial markers EMA, AE1/AE3, CK8, 18, 19, or for HER-2/neu, estrogen and progesterone receptors, as well as fluorescent IN SITU hybridization for HER-2/neu. The diagnosis of this tumor fulfills certain clinicopathological criteria. Mammary osteosarcoma is usually developed in phyllodes tumors or carcinosarcomas of the breast as a result of metaplasia of the epithelial component. This rare tumor of the breast is occasionally associated with prior radiation therapy or well documented trauma. Mammary osteosarcoma is a biologically aggressive neoplasm with a 38% five-year survival rate. Surgical resection is the most effective therapy to date. Adjuvant treatment -chemotherapy or radiotherapy- has shown no clear benefit. An extensive review of the literature is also presented. | es |
dc.format | application/pdf | es |
dc.format.extent | 5 | es |
dc.language | eng | es |
dc.publisher | Murcia : F. Hernández | es |
dc.relation.ispartof | Histology and histopathology | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Extraskeletal osteosarcoma | es |
dc.subject | Mammary gland | es |
dc.subject.other | 616 - Patología. Medicina clínica. Oncología | es |
dc.title | Primary mammary osteogenic sarcoma | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol.22, nº 4 (2007) |
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Fichero | Descripción | Tamaño | Formato | |
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Primary mammary osteogenic sarcoma.pdf | 2,32 MB | Adobe PDF | Visualizar/Abrir |
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