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https://doi.org/10.1016/j.diabres.2019.107871
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Título: | Trace elements in saliva and plasma of patients with type 2 diabetes: Association to metabolic control and complications |
Fecha de publicación: | 8-oct-2019 |
Editorial: | Elsevier Ltd. |
Cita bibliográfica: | Diabetes Research and Clinical Practice Volume 157, November 2019, 107871 |
ISSN: | Print: 0168-8227 |
Palabras clave: | Trace elements Saliva Plasma Type 2 diabetes mellitus |
Resumen: | Aim: An analysis is made of the saliva and plasma levels of trace elements in patients with type 2 diabetes mellitus and their association to metabolic control and the presence of chronic complications. Methods: A cross-sectional observational clinical study was carried out in 74 patients with type 2 diabetes mellitus. Mass spectrometry (ICP-MS) was used to determine the following trace elements in plasma and unstimulated basal saliva: 13Al, 16S, 4Be, 5B, 20Ca, 27Co, 29Cu, 24Cr, 38Sr, 15P, 3Li, 12Mg, 25Mn, 28Ni, 82Pb, 37Rb, 22Ti, 23V and 30Zn. Results: The levels of cobalt (p = 0.048) in saliva and of strontium (p = 0.001) in plasma were related to the presence of chronic complications. Significant differences with respect to metabolic control were observed for beryllium (p = 0.038), boron (p = 0.023) and phosphorus in saliva (p = 0.046), and for rubidium (p = 0.005), titanium (p = 0.016) and zinc in plasma (p = 0.013). A significant correlation (p < 0.001) was found between boron in plasma and boron in unstimulated basal saliva. Conclusions: The determination of trace elements in plasma and saliva constitutes a complementary tool for the assessment of metabolic control and for predicting chronic complications associated to type 2 diabetes mellitus. Further studies involving the biomonitoring of trace elements in saliva and plasma are needed |
Autor/es principal/es: | Marin Martinez, Luis Molino Pagan, Diana Lopez Jornet, Pia |
Facultad/Departamentos/Servicios: | Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Dermatología, Estomatología, Radiología y Medicina Física |
Versión del editor: | https://www.sciencedirect.com/science/article/pii/S0168822719310599?via%3Dihub |
URI: | http://hdl.handle.net/10201/137900 |
DOI: | https://doi.org/10.1016/j.diabres.2019.107871 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 8 |
Derechos: | info:eu-repo/semantics/embargoedAccess |
Descripción: | © 2019. Elsevier Ltd. This document is the Published version of a published work that appeared in final form in Diabetes Research and Clinical Practice. To access the final edited and published work see https://doi.org/To access the final edited and published work see https://doi.org/10.1016/j.knosys.2021.107394 |
Aparece en las colecciones: | Artículos: Dermatología, Estomatología, Radiología y Medicina Física |
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