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dc.contributor.authorMarin Martinez, Luis-
dc.contributor.authorMolino Pagan, Diana-
dc.contributor.authorLopez Jornet, Pia-
dc.contributor.otherFacultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Dermatología, Estomatología, Radiología y Medicina Físicaes
dc.date.accessioned2024-01-29T08:06:21Z-
dc.date.available2024-01-29T08:06:21Z-
dc.date.issued2019-10-08-
dc.identifier.citationDiabetes Research and Clinical Practice Volume 157, November 2019, 107871es
dc.identifier.issnPrint: 0168-8227-
dc.identifier.urihttp://hdl.handle.net/10201/137900-
dc.description© 2019. Elsevier Ltd. This document is the Published version of a published work that appeared in final form in Diabetes Research and Clinical Practice. To access the final edited and published work see https://doi.org/To access the final edited and published work see https://doi.org/10.1016/j.knosys.2021.107394es
dc.description.abstractAim: An analysis is made of the saliva and plasma levels of trace elements in patients with type 2 diabetes mellitus and their association to metabolic control and the presence of chronic complications. Methods: A cross-sectional observational clinical study was carried out in 74 patients with type 2 diabetes mellitus. Mass spectrometry (ICP-MS) was used to determine the following trace elements in plasma and unstimulated basal saliva: 13Al, 16S, 4Be, 5B, 20Ca, 27Co, 29Cu, 24Cr, 38Sr, 15P, 3Li, 12Mg, 25Mn, 28Ni, 82Pb, 37Rb, 22Ti, 23V and 30Zn. Results: The levels of cobalt (p = 0.048) in saliva and of strontium (p = 0.001) in plasma were related to the presence of chronic complications. Significant differences with respect to metabolic control were observed for beryllium (p = 0.038), boron (p = 0.023) and phosphorus in saliva (p = 0.046), and for rubidium (p = 0.005), titanium (p = 0.016) and zinc in plasma (p = 0.013). A significant correlation (p < 0.001) was found between boron in plasma and boron in unstimulated basal saliva. Conclusions: The determination of trace elements in plasma and saliva constitutes a complementary tool for the assessment of metabolic control and for predicting chronic complications associated to type 2 diabetes mellitus. Further studies involving the biomonitoring of trace elements in saliva and plasma are neededes
dc.formatapplication/pdfes
dc.format.extent8es
dc.languageenges
dc.publisherElsevier Ltd.es
dc.relationSin fianciacion externa a la Universidades
dc.rightsinfo:eu-repo/semantics/embargoedAccesses
dc.subjectTrace elementses
dc.subjectSalivaes
dc.subjectPlasmaes
dc.subjectType 2 diabetes mellituses
dc.titleTrace elements in saliva and plasma of patients with type 2 diabetes: Association to metabolic control and complicationses
dc.typeinfo:eu-repo/semantics/articlees
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S0168822719310599?via%3Dihubes
dc.embargo.termsSi-
dc.identifier.doihttps://doi.org/10.1016/j.diabres.2019.107871-
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