Browsing by Subject "Wound"

Now showing 1 - 2 of 2
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    Antibacterial effect of Spanish honeys of different botanical origins against Staphylococcus epidermidis
    (MDPI, 2024-06-15) Núñez Gómez, Vanesa; San Mateo Molina, Marta; Sánchez Martínez, Lorena; Periago Castón, María Jesús; Tecnología de Alimentos, Nutrición y Bromatología; Facultad de Veterinaria
    Honey is traditionally used for its medicinal properties attributed to its antibacterial and antioxidant effects. It is considered a natural alternative to conventional antibiotics. This effect has been attributed to their physico-chemical properties, as various chemical parameters can synergistically influence this effect. The aim of this study is to assess Spanish honeys of diverse botanical origins for their antibacterial efficacy against Staphylococcus epidermidis, correlating their physico-chemical attributes, (poly)phenol content, and antioxidant activity. The methods included colour determination via two methodologies, acidity, pH, moisture content, and sugar concentration. (Poly)phenol content was quantified using the Folin-Ciocalteau method, while antioxidant activity was evaluated via the FRAP method. Subsequently, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against S. epidermidis were investigated with different concentrations of honeys. The results revealed a direct relationship between honey darkness, (poly)phenol concentration, antioxidant activity, and antibacterial efficacy. Darker honeys exhibited higher (poly)phenol levels, greater antioxidant activity, and consequently, lower MIC and MBC values, showing enhanced antibacterial properties. These findings underscore the potential of honey as a therapeutic agent against S. epidermidis, particularly in wound healing applications to avoid infection. Further research into honey’s multifaceted properties is warranted to unveil novel therapeutic avenues in healthcare
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    Physical therapy in burn wound healing: Development of clinical prediction rules to identify the efficacy of pulsed electromagnetic therapy
    (Universidad de Murcia, Servicio de publicaciones, 2024) Nagy, Ahmed Mohamed; Elsayeh, Shaimaa Mohamed Ahmed; Bayoumi, Mohamed Bayoumi Ibrahim; Metawee, Shimaa Mohamed; Ahmed, Omnia Saeed Mahmoud; Saafan, Karim Ibrahim
    Many studies have demonstrated the effect of pulsed electromagnetic therapy (PEMT) on wound healing. This study aimed to develop a clinical prediction rule (CPR) to assess PEMT's efficacy in burn healing, potentially enhancing treatment decisions and outcomes. It was a one-group intervention study with 46 patients (21 males, 25 females) aged 20 to 55 years, having partial-thickness burns in the first or second healing stage, and a total burned surface area (TBSA) over 15%. The intervention involved pulsed electromagnetic therapy (Fisioline, Italy) for up to six weeks, with 60-minute sessions at 12 Hz and 12 Gauss, three times per week. The statistical analysis was conducted using the SPSS. The study revealed a significant decline in wound surface area (WSA) post-intervention (p < 0.05). A significant negative relationship was found between wound improvement and both age and total body surface area (TBSA) (p < 0.05), while a significant positive relationship was observed between wound improvement and initial wound size (p < 0.05). No significant relationship was found between wound improvement and wound stage (p > 0.05). The study concluded that pulsed electromagnetic therapy significantly reduces wound surface area. Additionally, age, TBSA, and initial burn wound size are important predictors of the therapy's efficacy in treating burn wounds.