(Universidad de Murcia. Departamento de Biología Celular e Histología, 2019) Wang, Shuwei; Yin, Yutong; Liu, Shuang
Glioma is the most common and aggressive
type of brain tumor. It has a poor prognosis and a high
recurrence rate. Despite continued advances in surgery,
chemotherapy and radiotherapy, the clinical outcomes
remain dismal. MicroRNAs (miRNAs) play important
roles in the initiation and progression of a multitude of
tumors. Until now, the molecular mechanism that is
responsible for glioma tumorigenesis and progression
remains unclear. Increasing evidence has shown that
miRNAs play an important role in glioma. In this
review, we focus on the current advances in determining
the role of miRNAs in regulating tumorigenesis and the
progression of glioma. In addition, the relevant roles of
miRNAs about