Datos de Investigación

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https://digitum.um.es/handle/10201/37686
El objetivo de esta comunidad es poner a disposición de los usuarios aquellos materiales generados o recolectados durante el transcurso de una investigación.

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Browsing Datos de Investigación by Subject "Aquaculture"

Now showing 1 - 4 of 4
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    Publication
    Open Access
    Bioinformatic and gene expression analysis of the somatostatin/cortistatin gene family in the gilthead seabream (Sparus aurata).
    Campos Sánchez, Jose Carlos; Serna‑Duque, Jhon A.; Guardiola, Francisco A.; Cuesta, Alberto; Esteban Abad, María Ángeles; Biología celular e Histología
  • Repository logo
    Publication
    Open Access
    Dataset used for the article: "Temporal dynamics of inflammation in gilthead seabream (Sparus aurata) induced by λ-carrageenan, LPS, and Poly I:C: from behaviour to gene expression"
    (2024-07-11) Campos Sánchez, Jose Carlos; Cabrera-Álvarez, Maria José; Oliveira, Ana Rita; Duarte Oliveira, Gonçalo; Guardiola, Francisco A.; Esteban, María Ángeles; Soares, Florbela; Saraiva , João L.; Departamento de Biología Celular e Histología
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    Publication
    Open Access
    Effects of cantharidin on fish erythrocytes, tumour cell lines, and marine pathogenic bacteria
    Campos-Sánchez, José Carlos; Guardiola, Francisco A.; Esteban Abad, María Ángeles; Biología celular e Histología
    Cantharidin, a toxic monoterpene secreted by blister beetles, has long been used in traditional Chinese and modern medicine for its unique properties. However, despite its widespread use, its effects on fish have not been studied in depth. The aim of this study was to evaluate the potential therapeutic applications of cantharidin in fish by examining its antioxidant, hemoagglutinating, hemolytic and cytotoxic activities at different concentrations (0, 0.625, 1.25, 2.5, 5 and 10 μg mL-1) in three different cell lines. In addition, the study explored the bactericidal and bacteriostatic properties of cantharidin against various fish pathogenic bacteria. The results revealed that there were no significant differences in antioxidant, hemagglutinating or hemolytic activities between the different concentrations of cantharidin tested. However, the study found that cantharidin exhibited dose- and time-dependent cytotoxicity in sea bream (Sparus aurata) erythrocytes and in SAF-1, PLHC-1 and Hela cell lines, resulting in morphological changes indicative of apoptosis. Interestingly, the highest dose of cantharidin tested demonstrated potent bactericidal activity against four marine fish opportunistic bacteria, including Vibrio harveyi, V. anguillarum, Photobacterium damselae and Tenacibaculum maritimum, but no statistically significant changes in bacteriostatic activity were observed against any of the bacteria tested. Overall, these results provide valuable information on the potential therapeutic applications of cantharidin in fish aquaculture. Further research is needed to fully understand the mechanisms of action and to explore possible preventive uses of cantharidin in fish.
  • Repository logo
    Publication
    Open Access
    Serum proteinogram of gilthead seabream (Sparus aurata) and European seabass (Dicentrarchus labrax) as a new useful approach for detecting loss of haemostasis
    Campos-Sánchez, Jose Carlos; Guardiola, Francisco A.; Esteban Abad, María Ángeles; Biología celular e Histología