(Murcia : F. Hernández, 2005) Wang, H.T.; Chang, J.W.
Bladder transitional cell carcinoma (BTCC)
actually has two phenotypes: low malignant and
aggressive. Most previous molecular and cytogenetic
analyses of bladder cancer were focused on aggressive
BTCC. Little is known about the events that lead to the
development of low malignant BTCC. This review
mainly introduces the concept of two types of bladder
tumors and then focuses on the molecular pathology of
low malignant BTCC in particular. It is hoped that
further understanding of the molecular pathology of low
malignant BTCC may provide novel therapies and many
other clinical benefits in patients with this disease.