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Título: | Anti-inflammatory and antifibrotic effects of resveratrol in the lung |
Fecha de publicación: | 2015 |
Editorial: | F. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de Biología Celular e Histología |
Cita bibliográfica: | Histology and Histopathology, Vol. 30, n.º 5 (2015) |
ISSN: | 1699-5848 0213-3911 |
Materias relacionadas: | CDU::5 - Ciencias puras y naturales::57 - Biología::576 - Biología celular y subcelular. Citología |
Palabras clave: | Acute lung injury Asthma COPD Fibrosis |
Resumen: | Resveratrol, a natural polyphenolic molecule with several biological activities, is a well recognized anti-oxidant, anti-aging and cancer chemopreventive agent. Moreover, resveratrol anti-inflammatory and antifibrotic properties have been demonstrated both in vitro and in different animal models of inflammatory pathologies, including bowel and liver diseases. We review the evidence of resveratrol protective role in respiratory diseases such as acute lung injury, asthma, chronic obstructive pulmonary disease and lung fibrosis. We conclude that resveratrol and its derivatives may act as a therapeutic agents in respiratory diseases and pertinent clinical trials should be performed. |
Autor/es principal/es: | Conte, Enrico Fagone, Evelina Fruciano, Mary Gili, Elisa Iemmolo, Maria Vancheri, Carlo |
URI: | http://hdl.handle.net/10201/90077 |
DOI: | https://doi.org/10.14670/HH-30.523 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 7 |
Derechos: | info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 International |
Aparece en las colecciones: | Vol.30, nº5 (2015) |
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Conte-30-523-529-2015.pdf | 1,63 MB | Adobe PDF | Visualizar/Abrir |
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