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Título: | Neurobiological toxicity of radiation in hippocampal cells |
Fecha de publicación: | 2013 |
Cita bibliográfica: | Histology and histopathology, Vol. 28, n.º 3 (2013) |
ISSN: | 1699-5848 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina::615 - Farmacología. Terapéutica. Toxicología. Radiología |
Palabras clave: | Cognition Radiation |
Resumen: | Worldwide radiation exposure is increasing due to recent nuclear accidents, space travel, atomic weapons testing and use, and medical treatments. In adult animals, ionizing radiation can significantly impact hippocampal neurogenesis and negatively affect hippocampal functions such as cognition. However, there is considerable uncertainty regarding the mechanisms underlying these effects. This article reviews in vivo and in vitro studies on the effects of irradiation on hippocampal neurogenesis and function in order to gain new mechanistic insights. This information will provide complementary views of our understanding of the normal brain’s tolerance to radiation exposure, the potentially serious implications of radiation exposure to cognition, and lead to a discussion of potential strategies for pharmacotherapy and behavioral intervention. |
Autor/es principal/es: | Kim, Joong-Sun Yang, Miyoung Kim, Sung-Ho Shin, Taekyun Moon, Changjong |
URI: | http://hdl.handle.net/10201/56137 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 10 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol.28, nº 3 (2013) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Kim-28-301-310-2013.pdf | 187,28 kB | Adobe PDF | Visualizar/Abrir |
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