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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Dousias, Vassilis | - |
dc.contributor.author | Vrekoussis, Thomas | - |
dc.contributor.author | Navrozoglou, Iordanis | - |
dc.contributor.author | Paschopoulos, Minas | - |
dc.contributor.author | Stefos, Theodore | - |
dc.contributor.author | Makrigiannakis, Antonis | - |
dc.contributor.author | Jeschke, Udo | - |
dc.date.accessioned | 2017-11-07T15:56:37Z | - |
dc.date.available | 2017-11-07T15:56:37Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | Histology and histopathology, Vol. 27, nº 10 (2012) | es |
dc.identifier.issn | 0213-3911 | - |
dc.identifier.issn | 1699-5848 | - |
dc.identifier.uri | http://hdl.handle.net/10201/54445 | - |
dc.description.abstract | Despite the well-established role of hypoxia in cancer biology, the literature on its effects on endometrial cancer is scarce; it mainly refers to experimental settings rather than patient-derived results. Herein, an overview of the hypoxia inducible factor 1α (HIF-1α) biology, focusing on endometrial cancer, is presented. The molecular mechanisms possibly involved in endometrial cancer progression are presented, followed by a systematic approach to the current literature on immunohistochemistry evaluation of HIF-1α expression in endometrial carcinoma. Since no consensus has been made regarding HIF-1α evaluation, the evidence of possible involvement of HIF-1α in endometrial carcinoma prognosis is weak. After a consensus has been made, properly powered studies may be able to clarify whether HIF-1α can act as a prognosticator in endometrial carcinoma. | es |
dc.format | application/pdf | es |
dc.format.extent | 7 | es |
dc.language | eng | es |
dc.publisher | F. Hernández y Juan F. Madrid. Universidad de Murcia. Departamento de Biología Celular e Histología | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Endometrial cancer | es |
dc.subject | Hypoxia | es |
dc.subject.other | CDU::5 - Ciencias puras y naturales::57 - Biología::576 - Biología celular y subcelular. Citología | es |
dc.title | Hypoxia-induced Factor-1α in endometrial carcinoma: a mini-review of current evidence | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol.27, nº10 (2012) |
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Dousias-27-1247-1252-2012.pdf | 503,76 kB | Adobe PDF | Visualizar/Abrir |
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