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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Tonon Veit, Ana Paula | - |
dc.contributor.author | Nelisis Zanoni, Jacqueline | - |
dc.date.accessioned | 2017-03-08T17:37:33Z | - |
dc.date.available | 2017-03-08T17:37:33Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | Histology and histopathology, Vol. 27, nº 1 (2012) | es |
dc.identifier.issn | 1699-5848 | - |
dc.identifier.issn | 0213-3911 | - |
dc.identifier.uri | http://hdl.handle.net/10201/52383 | - |
dc.description.abstract | We examined the effects of ascorbic acid supplementation on myosin-V, calcitonin gene-related peptide (CGRP) and vasoactive intestinal polypeptide (VIP) immunoractivities in the myenteric neurons in aging rats. Male rats were divided into groups: young 90-day-old rats (E90), 345-day-old control rats (E345), 428-day-old control rats (E428), 90- to 345-day-old rats treated with ascorbic acid (1 g/L) (EA345), and 90- to 428-day-old rats treated with ascorbic acid (1g/L) (EA428). The quantitative results showed that aging reduced the number of myosin-V-immunoreactive neurons compared with young animals (E90). Ascorbic acid supplementation in the EA345 and EA428 groups increased the average area of myosin-V neurons by 24.6% and 24.1% compared with the E345 and E428 groups, respectively. When all groups were compared, we observed significant differences for the CGRP- and VIP-immunoractive varicosities of nerve fibers from myenteric neurons. Ascorbic acid supplementation had a neurotrophic effect on all neurons studied, suggesting a neuroprotective role | es |
dc.format | application/pdf | es |
dc.format.extent | 10 | es |
dc.language | eng | es |
dc.publisher | F. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de Biología Celular e Histología | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Aging | es |
dc.subject | Ascorbic acid | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina | es |
dc.title | Age-related changes in myosin-V myenteric neurons, CGRP and VIP immunoreactivity in the ileum of rats supplemented with ascorbic acid | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol.27, nº 1 (2012) |
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Fichero | Descripción | Tamaño | Formato | |
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Veit-27-123-132-2012.pdf | 7,59 MB | Adobe PDF | Visualizar/Abrir |
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