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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Heman, Paola | - |
dc.contributor.author | Barcia, Carlos | - |
dc.contributor.author | Gómez, Aurora | - |
dc.contributor.author | Ros, Carmen M. | - |
dc.contributor.author | Ros Bernal, Francisco | - |
dc.contributor.author | Yuste Jiménez, José Enrique | - |
dc.contributor.author | Pablos, Vicente de | - |
dc.contributor.author | Fernández Villalba, Emiliano | - |
dc.contributor.author | Toledo Cárdenas, María Rebeca | - |
dc.contributor.author | Herrero Ezquerro, María Trinidad | - |
dc.date.accessioned | 2017-03-08T16:27:26Z | - |
dc.date.available | 2017-03-08T16:27:26Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | Histology and histopathology, Vol. 27, nº 1 (2012) | es |
dc.identifier.issn | 1699-5848 | - |
dc.identifier.issn | 0213-3911 | - |
dc.identifier.uri | http://hdl.handle.net/10201/52378 | - |
dc.description.abstract | In the present work we analyze the cerebellum of chronic parkinsonian monkeys in order to clarify whether chronic mesencephalic depletion is associated with long term activation of the cerebellar neurons in chronic Parkinsonism. In our study, we observed a persistent activation of Purkinje cells in the cerebellum of chronic parkinsonian macaques, characterized by the expression of c-Fos, which correlated with dopaminergic degeneration. These results are compatible with the results observed in fMRI in Parkinson’s disease patients, and may contribute to the understanding of additional alterations in the brain circuitry in Parkinsonism | es |
dc.format | application/pdf | es |
dc.format.extent | 6 | es |
dc.language | eng | es |
dc.publisher | F. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de Biología Celular e Histología | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Parkinson´s disease | es |
dc.subject | Cerebellum | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología::616.8 - Neurología. Neuropatología. Sistema nervioso | es |
dc.title | Nigral degeneration correlates with persistent activation of cerebellar Purkinje cells in MPTP-treated monkeys | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol.27, nº 1 (2012) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Heman-27-89-94-2012.pdf | 9,64 MB | Adobe PDF | Visualizar/Abrir |
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