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Title: DNA repair mechanisms in mammalian germ cells
Issue Date: 2011
Publisher: Murcia: F. Hernández
ISSN: 1699-5848
Related subjects: 61 - Medicina
Keywords: Germ cells
Gene expression
Abstract: Mammalian germ cells encounter several types of DNA damage. This damage is almost completely repaired in a short period of time to provide the maintenance of genomic integrity. The main repair mechanisms operating in mammalian germline cells are: nucleotide excision repair (NER), base excision repair (BER), mismatch repair (MMR), DNA double strand break repair (DSBR), and post replication repair (PRR). Currently, there are relatively few publications that summarize basic information and new findings on DNA repair mechanisms used in mammalian germ cells. In the present article, we review the studies that discuss repair mechanisms operating in the female and male germ cells. We then survey some of the recent discoveries made in this field.
Primary author: Ozturk, Saffet
Demir, Necdet
Published in: Histology and histopathology, Vol. 26, nº 4 (2011)
Document type: info:eu-repo/semantics/article
Number of pages / Extensions: 13
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:Vol.26, nº4 (2011)

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