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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Módis Jr, László | es |
dc.contributor.author | Szalai, Eszter | es |
dc.contributor.author | Kertész, Katalin | - |
dc.contributor.author | Kemény-Beke, Ádám | - |
dc.contributor.author | Kettesy, Beáta | - |
dc.contributor.author | Berta, Andras | - |
dc.date.accessioned | 2015-09-29T07:19:06Z | - |
dc.date.available | 2015-09-29T07:19:06Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0213-3911 | es |
dc.identifier.uri | http://hdl.handle.net/10201/46374 | - |
dc.description.abstract | Background: The aim of the present study is to determine corneal physiology and endothelial morphology after proper image analysis technique in type I and II diabetic patients. The HbA1c level and the grade of retinopathy were also recorded and correlated with the endothelial parameters. Methods: 41 eyes of 21 patients with type I and 59 eyes of 30 patients with type II diabetes mellitus (mean age was 40.97±15.46 and 64.36±10.47 years) were examined and compared to age-matched controls. Endothelial cell density (ECD), mean cell area, coefficient of variation of cell area, central corneal thickness, intraocular pressure, and grade of retinopathy were recorded. Results: There was a statistically significant decreased endothelial cell density in type I disease (2428±219 cell/mm2) in comparison with healthy subjects (2495±191 cell/mm2, P=0.02). The diabetic corneas were thicker than normal (P=0.001). The HbA1c level was inversely correlated with the ECD (r=-0.60; P<0.0001) and correlated with the mean endothelial cell area (r=0.60, P<0.0001). Significant correlation was observed between the endothelial morphology and grade of diabetic retinopathy (r=-0.40, ECD; r=0.38, mean cell area; P=0.01 for both). In type II diabetes mellitus no significant difference was found in the evaluated values. Conclusions: The present study disclosed the alteration of the corneal endothelial morphology in type I diabetes mellitus as compared to normal subjects. The results indicated that type I diabetic corneas are more susceptible to environmental changes than type II corneas. | es |
dc.format | application/pdf | es |
dc.format.extent | 7 | es |
dc.language | eng | es |
dc.publisher | Murcia : F. Hernández | es |
dc.relation.ispartof | Histology and histopathology | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Diabetes mellitus | es |
dc.subject | Corneal endothelial morphology | es |
dc.subject.other | 61 - Medicina | es |
dc.title | Evaluation of the corneal endothelium in patients with diabetes mellitus type I and II | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol.25,nº12 (2010) |
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Fichero | Descripción | Tamaño | Formato | |
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Evaluation of the corneal endothelium in patients with diabetes mellitus type I and II.pdf | 617,49 kB | Adobe PDF | Visualizar/Abrir |
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