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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Navarro, Ana | es |
dc.contributor.author | Ordóñez, Cristina | es |
dc.contributor.author | Martinez, Eva | - |
dc.contributor.author | Pérez, Cristina | - |
dc.contributor.author | Astudillo, Aurora | - |
dc.contributor.author | Tolivia, Jorge | - |
dc.date.accessioned | 2013-01-18T13:36:20Z | - |
dc.date.available | 2013-01-18T13:36:20Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0213-3911 | es |
dc.identifier.uri | http://hdl.handle.net/10201/29721 | - |
dc.description.abstract | Apolipoprotein D (apo D), a lipocalin transporter of small hydrophobic molecules could play an important role in several neurodegenerative diseases. However, its role in those diseases remains unclear. There has been reported increments of apo D in relation with different neuropathologic diseases. Recently, we reported the absence of apo D in neurons of substantia nigra which can contribute to the lability of neurons to oxidative damage. In order to determine the relationship between apo D expression and neuronal death, we studied the expression of apo D in various regions of human brains from patients without any neurological or psychological disorders, in relation with the neuronal damage revealed by Fluoro-Jade B staining. The absence of expression for apo D in injured neurons and the negative staining for Fluoro-Jade B of neurons that express apo D was observed in all sections studied. These findings are in accordance with the role possibly played by apo D in the neuroprotection of the nervous system. | es |
dc.format | application/pdf | es |
dc.format.extent | 7 | es |
dc.language | eng | es |
dc.publisher | Murcia : F. Hernández | es |
dc.relation.ispartof | Histology and histopathology | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Histochemistry | es |
dc.subject | Immunohistochemistry | es |
dc.subject.other | 576 - Biología celular y subcelular. Citología | es |
dc.title | Apolipoprotein D expression absence in degenerating neurons of human central nervous system | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol.23, nº8 (2008) |
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Fichero | Descripción | Tamaño | Formato | |
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Apolipoprotein D expression absence in degenerating neurons of human central nervous system.pdf | 2,63 MB | Adobe PDF | Visualizar/Abrir |
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