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http://hdl.handle.net/10201/27610
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Fritzsche, F.R. | es |
dc.contributor.author | Dahl, E. | es |
dc.contributor.author | Dankof, A. | - |
dc.contributor.author | Burkhardt, M. | - |
dc.contributor.author | Pahl, S. | - |
dc.contributor.author | Petersen, I. | - |
dc.contributor.author | Dietel, Manfred | - |
dc.contributor.author | Kristiansen, Gitte | - |
dc.date.accessioned | 2012-05-21T12:10:19Z | - |
dc.date.available | 2012-05-21T12:10:19Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 0213-3911 | es |
dc.identifier.uri | http://hdl.handle.net/10201/27610 | - |
dc.description.abstract | We aimed to evaluate immunohistochemically the expression of the human Anterior Gradient-2 (AGR2), a gene which has recently been proposed as an oncogene for lung carcinoma development, in non small cell lung cancer and to correlate the findings to clinico-pathological data including patient survival. 95 cases of NSCLC were immunostained using a polyclonal AGR2 antibody and statistical analyses were applied to test for prognostic and diagnostic associations. AGR2 was expressed in 66.3% of cases, preferentially adenocarcinomas. There were no relevant associations with clinico-pathological paramaters. A prognostic value of AGR2 could not be demonstrated neither in multivariate nor in univariate analyses. Interestingly, this is the first study to demonstrate AGR2 expression in squamous cell carcinomas. Although a prognostic value of AGR2 seems unlikely further studies are warranted to investigate the biological role of AGR2 in NSCLC and its differential expression according to histology. | es |
dc.format | application/pdf | es |
dc.format.extent | 6 | es |
dc.language | eng | es |
dc.publisher | Murcia : F. Hernández | es |
dc.relation.ispartof | Histology and histopathology | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Lung cancer | es |
dc.subject | Immunohistochemistry | es |
dc.subject.other | 616 - Patología. Medicina clínica. Oncología | es |
dc.title | Expression of AGR2 in non small cell lung cancer | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol.22, nº 7 (2007) |
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Fichero | Descripción | Tamaño | Formato | |
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Expression of AGR2 in non small cell lung cancer.pdf | 2,28 MB | Adobe PDF | ![]() Visualizar/Abrir |
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