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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.advisor | Larqué Daza, Elvira | - |
dc.contributor.advisor | Parrilla Paricio, Juan José | - |
dc.contributor.advisor | Koletzko, Berthold | - |
dc.contributor.author | Gil Sánchez, Alfonso | - |
dc.contributor.other | Departamentos y Servicios::Departamentos de la UMU::Cirugía, Pediatría y Obstetricia y Ginecología | es |
dc.date.accessioned | 2011-09-21T12:15:27Z | - |
dc.date.available | 2011-09-21T12:15:27Z | - |
dc.date.created | 2011-06-30 | - |
dc.date.issued | 2011-09-21 | - |
dc.identifier.uri | http://hdl.handle.net/10201/24780 | - |
dc.description.abstract | A supply of omega-3 long-chain polyunsaturated fatty acids (LC-PUFA) is essential for fetal development. Objective: We assessed placental transfer of 13C-labelled fatty acids (FA) 12 hours after oral application. Design: 11 pregnant women received 12h before elective caesarean section 0.5mg/kg 13C-palmitic acid (PA, 16:0), 13C-oleic acid (OA, 18:1n-9), 13C-linoleic acid (LA, 18:2n-6) and 0.1mg/kg 13C-docosahexaenoic acid (DHA, 22:6n-3) orally. Maternal blood samples, venous cord blood and placental tissue were collected and FA concentrations and their tracer content determined. Results: Most 13C-PA and 13C-OA in maternal plasma were in triglycerides (TG), while 13C-LA and 13C-DHA were mainly found in both plasma phospholipids and TG. Placenta/maternal plasma ratios and fetal/maternal plasma ratios for 13C-DHA were higher than for any other FA. Conclusions: We found a significantly higher ratio of 13C-DHA concentrations between cord to maternal plasma than for the other FA, in agreement with preferential transfer of DHA across the placenta. | es |
dc.format | application/pdf | es |
dc.format.extent | 195 | es |
dc.language | spa | es |
dc.publisher | Universidad de Murcia | es |
dc.relation.ispartof | Proyecto de investigación: | es |
dc.relation.replaces | http://hdl.handle.net/10803/37470 | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Ginecología | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina::618 - Ginecología. Obstetricia | es |
dc.title | Investigación in vivo de la transferencia placentaria de ácidos grasos marcados con carbono 13 en humanos | es |
dc.type | info:eu-repo/semantics/doctoralThesis | es |
Aparece en las colecciones: | Ciencias de la Salud |
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Fichero | Descripción | Tamaño | Formato | |
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TAGS.pdf | 15,49 MB | Adobe PDF | Visualizar/Abrir |
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