Por favor, use este identificador para citar o enlazar este ítem:
http://hdl.handle.net/10201/22637
Twittear
Título: | The transcription factor E2F: a crucial switch in the control of homeostasis and tumorigenesis |
Fecha de publicación: | 2006 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina |
Palabras clave: | Apoptosis Tumorigenesis |
Resumen: | The transcription factor E2F plays a crucial role in governing cell proliferation through manipulation of the expression of many genes required for cell cycle progression. As studies are exploring in depth, E2F has grown into a multimember family and has been required for the regulation of a large number of genes involved in various cellular processes. The expanding E2F membership and biological function provide us some new insights relating to the evolution of E2F. One of them is to understand the exact mechanisms by which E2F executes in these different cellular processes during ontogenesis. This review summarizes recent advances in this field, with an emphasis on a notion that E2F acts as a molecular switch in the control of both normal cell and tumor development. |
Autor/es principal/es: | Fang, Z.H. Han, Z.C. |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/22637 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 11 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol.21, nº 4 (2006) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
The transcription factor E2F a crucial switch in the control of homeostasis and tumorigenesis.pdf | 613,71 kB | Adobe PDF | Visualizar/Abrir |
Los ítems de Digitum están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.