Por favor, use este identificador para citar o enlazar este ítem:
http://hdl.handle.net/10201/21531
Twittear
Registro completo de metadatos
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Gheri, G. | es |
dc.contributor.author | Vannelli, G.B. | es |
dc.contributor.author | Marini, M. | - |
dc.contributor.author | Zappoli Thyrion, G.D. | - |
dc.contributor.author | Gheri, R.G. | - |
dc.contributor.author | Sgambati, E. | - |
dc.date.accessioned | 2011-06-08T09:04:44Z | - |
dc.date.available | 2011-06-08T09:04:44Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 0213-3911 | es |
dc.identifier.uri | http://hdl.handle.net/10201/21531 | - |
dc.description.abstract | In the present research we have investigated the distribution of the sugar residues of the glycoconjugates in the prepubertal and postpubertal testes of a subject with Morris’s syndrome (CAIS, Complete Androgen Insensitivity Syndrome). For this purpose a battery of six horseradish peroxidaseconjugated lectins was used (SBA, PNA, WGA, ConA, LTA and UEAI). We have obtained a complete distributional map of the terminal and sub-terminal oligosaccharides in the tunica albuginea, interstitial tissue, lamina propria of the seminiferous tubules, Leydig cells, Sertoli cells, spermatogonia, mastocytes and endothelial cells. Furthermore the present study has shown that a large amount of sugar residues were detectable in the prepubertal and postpubertal testes but that some differences exist with particular regard to the Sertoli cells. The Sertoli cells and the Leydig cells of the retained prepubertal testis of the patient affected by Morris’s syndrome were characterized by the presence of a-L-fucose, which was absent in the retained prepubertal testis of the normal subjects. Comparing the results on the postpubertal testis with those obtained on the same aged testis of healthy subjects we have demonstrated that a-L-fucose in the Sertoli and Leydig cells and D-galactose-N-acetyl-D-galactosamine in the results on the postpubertal testis with those obtained on the same aged testis of healthy subjects we have demonstrated that a-L-fucose in the Sertoli and Leydig cells and D-galactose-N-acetyl-D-galactosamine in the Leydig cells are a unique feature of the subject affected by Morris’s syndrome. D-galactose (ß1?3)-N-acetyl-Dgalactosamine and sialic acid, which are present in the Leydig cells of the normal testis were never observed in the same cells of the postpubertal testis of the CAIS patient. | es |
dc.format | application/pdf | es |
dc.format.extent | 8 | es |
dc.language | eng | es |
dc.publisher | Murcia : F. Hernández | es |
dc.relation.ispartof | Histology and histopathology | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Oligosaccharides | es |
dc.subject | Morris’s syndrome | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina::611 - Anatomía | es |
dc.title | Distributional map of the terminal and sub-terminal sugar residues of the glycoconjugates in the prepubertal and postpubertal testis of a subject affected by complete androgen insensitivity syndrome (Morris’s syndrome): lectin histochemical study | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol.19, nº 1 (2004) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
Distributional map of the terminal and.pdf | 2,6 MB | Adobe PDF | Visualizar/Abrir |
Los ítems de Digitum están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.