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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Seagal, J. | es |
dc.contributor.author | Melamed, D. | es |
dc.date.accessioned | 2011-06-08T09:03:01Z | - |
dc.date.available | 2011-06-08T09:03:01Z | - |
dc.date.issued | 2003 | - |
dc.identifier.issn | 0213-3911 | es |
dc.identifier.uri | http://hdl.handle.net/10201/21433 | - |
dc.description.abstract | Homeostasis in the B cell compartment (as well as in T cells) is controlled by tightly regulated selection events. Throughout their life span, B cells are subjected to selection signals determining not only developmental progression, but also maturation and survival. It is now clear that most of these signals require the expression of B cell antigen receptor (or preB receptor) with functional signaling capacity. The administration of numerous mutations into the mouse germline enabled us to identify several checkpoints along the B cell developmental pathway, and provided us with powerful experimental tools to probe for selection events regulating developmental progression. In here, we will discuss recent studies in this field. | es |
dc.format | application/pdf | es |
dc.format.extent | 9 | es |
dc.language | eng | es |
dc.publisher | Murcia : F. Hernández | es |
dc.relation.ispartof | Histology and histopathology | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Positive selection | es |
dc.subject | Negative selection | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina | es |
dc.title | Selection events in directing B cell development | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol.18, nº 2 (2003) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Selection events in directing B cell development.pdf | 338,16 kB | Adobe PDF | Visualizar/Abrir |
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