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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Nara, S. | es |
dc.contributor.author | Hachisuka, K. | es |
dc.contributor.author | Furukawa, H. | - |
dc.contributor.author | Doi, Y. | - |
dc.contributor.author | Kudo, H. | - |
dc.contributor.author | Fujimoto, S. | - |
dc.date.accessioned | 2011-05-11T10:58:09Z | - |
dc.date.available | 2011-05-11T10:58:09Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 0213-3911 | es |
dc.identifier.uri | http://hdl.handle.net/10201/20786 | - |
dc.description.abstract | Immunoreactivity for desmin, plectin and a- actinin was inve s t i gated in rat atrophic soleus muscle fibers induced by hindlimb suspension between 1 and 4 weeks (hindlimb suspension group, HSG), and compared with that of the control group (CG). Some of the HSG for 4 weeks were allowed unrestricted cage activity for 2 weeks as the recovery group (RG). In the cross-sectioned muscle fibers of the CG, desmin and plectin show e d h o n ey-comb immunoreactive patterns ex t e n d i n g throughout the sarcoplasm. Superimposed images by double immunofluorescence labeling show e d overlapping of both immunoreactivities. In the longitudinally sectioned profiles, superimposed images of a-actinin and desmin were overlapped at the level of Z-discs. The focal disorganization of the above honey - comb immunoreactive patterns, followed by the reduction of the cross-sectional area (CSA) of atrophic soleus muscle fibers and the appearance of Z-streaming, uniquely arose in the HSG from the first week and extended throughout the sarcoplasm in proportion to the suspension period. Such honey-comb patterns of both desmin and plectin were already restored in the RG at 2 weeks, followed by the disappearance of Z-streaming, prior to the recovery of the CSA. These findings indicate that the disorganization of topological and structural relationships of desmin and plectin with Z-discs surrounding individual myofibrils is primarily evo ke d , which leads to Z-streaming of atrophic soleus muscle fibers, and that the restoration of the muscle activity results in an early arrangement recovery of desmin and plectin around myofibrils. | es |
dc.format | application/pdf | es |
dc.format.extent | 10 | es |
dc.language | eng | es |
dc.publisher | Murcia : F. Hernández | es |
dc.relation.ispartof | Histology and histopathology | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Desmin | es |
dc.subject | Muscle atrophy | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina::611 - Anatomía | es |
dc.title | Disorganization of honey-comb immunoreactive pattern of desmin and plectin in rat atrophic soleus muscle fiber induced by hindlimb suspension | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol.17, nº 2 (2002) |
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Disorganization of honeycomb immunoreactive pattern of desmin and plectin in rat atrophic soleus muscle fiber induced by hindlimb suspension.pdf | 748,47 kB | Adobe PDF | Visualizar/Abrir |
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