Please use this identifier to cite or link to this item: http://hdl.handle.net/10201/20780

Title: Effects of cigarette smoke exposure on the utlrastructure of the golden hamster parathyroid gland
Issue Date: 2002
Publisher: Murcia : F. Hernández
ISSN: 0213-3911
Related subjects: CDU::6 - Ciencias aplicadas::61 - Medicina::611 - Anatomía
Keywords: Parathyroid gland
Smoking
Abstract: Cigarette smoking has been identified as one of the risk factors to induce osteoporosis. However, we find no study on the morphology of the parathy r o i d gland under smoking exposure. We studied the ultrastructure of the parathyroid gland, lung and femur of the golden hamster exposed to cigarette smoke. Fourweek- old male hamsters were housed in a plastic case (48x31x30 cm) and were exposed to cigarette smoke for 12 weeks, 5 minutes exposure, 4 times a day, 4 days a week. There were no differences in serum calcium level and the whole bone mineral density between the control and the smoke-exposed groups. In the parathyroid gland of the smoke - exposed animals, the Golgi complexe s associated with many prosecretory granules were well d eveloped and many secretory granules were located near the plasma membrane. Large lipid-like inclusion bodies were observed in the alveolar macrophages of the smoke-exposed animals. The femur morphology showed a wider area of resorbing surface in the smoke-exposed group than in the control group. From these findings, it is conceivable that the secretory activity of the p a r a t hyroid gland was stimulated with cigarette smoke exposure.
Primary author: Yano, R.
Hayakawa, D.
Emura, S.
chen, H.
Ozawa, Y.
Taguchi, H.
Shoumura, S.
Published in: Histology and histopathology
URI: http://hdl.handle.net/10201/20780
Document type: info:eu-repo/semantics/article
Number of pages / Extensions: 7
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:Vol.17, nº 2 (2002)

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