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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Arvanitis, D. | es |
dc.contributor.author | Kamper, E.F. | es |
dc.contributor.author | Kopeikina, L. | - |
dc.contributor.author | Stavridou, A. | - |
dc.contributor.author | Sgantzos, M. | - |
dc.contributor.author | Kallioras, V. | - |
dc.contributor.author | Athanassiou, E.D. | - |
dc.contributor.author | Kanavaros, Panagiotis | - |
dc.date.accessioned | 2011-05-11T10:57:57Z | - |
dc.date.available | 2011-05-11T10:57:57Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 0213-3911 | es |
dc.identifier.uri | http://hdl.handle.net/10201/20772 | - |
dc.description.abstract | A i m s : The aim was to analyze the immunohistochemical localization of tetranectin in gastric adenocarcinomas and the adjacent tissues of the wall of the stomach. Methods and results: Forty cases of gastric adenocarcinomas were stained by the indirect immunoperoxidase method. Of the ten cases of mucinous signet ring cell carcinomas 5 showed high, 3 moderate and 2 low tetranectin expression. Of the ten cases of well-differentiated intestinal type adenocarcinomas (ITA) 4 showed moderate regional, 3 l ow regional and 3 nega t ive tetranectin expression. Of the ten cases of moderately-differentiated ITA 3 showed moderate regional, 4 low regional and 3 nega t ive tetranectin expression. Of the ten cases of poorlyd i fferentiated ITA 4 showed focal low and 6 nega t ive tetranectin expression. Overall, the mucinous signet ring carcinomas showed significantly higher tetranectin expression compared to ITA (c2=3.95, p<0.05). In contrast, no significant relationship was found between tetranectin expression and the degree of differentiation in I TA (c2=2.5, p>0.05). In all cases, the perineoplastic desmoplastic reactive stroma showed high expression of tetranectin intra- and extracellularly. The mast cells and goblet cells in the areas of intestinal metaplasia showed high tetranectin expression. C o n c l u s i o n s : This study s h ows that: a) tetranectin is produced and deposited extracellularly in the desmoplastic peritumoral stroma of i n filtrating gastric adenocarcinomas; b) tetranectin is more highly expressed by the mucinous signet ring cell carcinomas compared to ITA; and c) the amount of tetranectin produced by the ITA is unrelated with the degree of tumor differentiation. | es |
dc.format | application/pdf | es |
dc.format.extent | 5 | es |
dc.language | eng | es |
dc.publisher | Murcia : F. Hernández | es |
dc.relation.ispartof | Histology and histopathology | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Adenocarcinoma | es |
dc.subject | Stomach | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología::616.3 - Patología del aparato digestivo. Odontología | es |
dc.title | Tetranectin expression in gastric adenocarcinomas | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol.17, nº 2 (2002) |
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Tetranectin expression in gastric adenocarcinomas.pdf | 91,56 kB | Adobe PDF | Visualizar/Abrir |
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