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Título: Vascular and stromal changes in irradiated and recovering rat thymus
Fecha de publicación: 1999
Editorial: Murcia : F. Hernández
ISSN: 0213-3911
Materias relacionadas: CDU::6 - Ciencias aplicadas::61 - Medicina
Palabras clave: Thymus
Vascular structure
Resumen: To analyze the mechanisms responsible for thymocyte proliferation, maturation and migration in the thymus, the rat thymus just after, and recovering from irradiation was studied morphologically. The vascular structures of the rat thymus after a radiation dose of 6 Gy were found to be destroyed on day 3, but had recovered to almost normal by day 7, suggesting that the abrupt recovery of thymus structure after irradiation was due primarily to this change in vascular structure. Furthermore, the epithelial tissues in the thymic cortex appeared to contribute to this abrupt proliferation, and possibly to the abrupt maturation of thymocytes, while medullary epithelial tissues remained sparse and appeared inactive for a relatively long period. These findings are considered important for understanding the interrelationship between thymic epithelial cells and thymocytes with respect to thymocyte proliferation, maturation and migration.
Autor/es principal/es: Wang, Y.L.
Tokuda, N.
Tamechika, M.
Hashimoto, N.
Yamauchi, M.
Kawamura, H.
Irifune, T.
Choi, M.
Awaya, A.
Sawada, T.
Fukumoto, T.
Publicado en: Histology and histopathology
URI: http://hdl.handle.net/10201/19211
Tipo de documento: info:eu-repo/semantics/article
Número páginas / Extensión: 6
Derechos: info:eu-repo/semantics/openAccess
Aparece en las colecciones:Vol.14, nº 3 (1999)

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