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Título: | Mammalian spermatogenesis investigated by genetic engineering |
Fecha de publicación: | 1999 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina |
Palabras clave: | Meiosis Spermatogenesis |
Resumen: | Genes involved in mammal spermatogenesis can now be identified through mutants created by genetic engineering. Information has been obtained on male meiosis, but also on the factors regulating the proliferation, maintenance and differentiation of male germ cells. Its has also increased our knowledge of the germ cell phenotype emerging from an altered germ cell genotype. This review is focused on data from genes expressed in male germ cells and on the question of how germ cells and Sertoli cells cope with the molecular lesions induced. The conservation of a wild-type phenotype of male germ cells in mutant mice is discussed, and how the mouse genetic background can lead to different germ cell phenotypes for a given gene mutation. |
Autor/es principal/es: | Escalier, D. |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/19209 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 14 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol.14, nº 3 (1999) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Mammalian spermatogenesis investigated by genetic engineering.pdf | 265,44 kB | Adobe PDF | Visualizar/Abrir |
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